雷建都

点击数:   更新日期: 2018-04-04

雷建都   教授、博士生导师


性 别:男

电子邮箱ljd2012@bjfu.edu.cn

办公电话010-62337251

研究方向:纳米药物与功能材料

详细资料

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教育/工作经历

2012-现在,北京林业大学材料科学与技术学院,教授

2004-2012中国科学院过程工程研究所,助研、副研、研究员

2002-2004清华大学化学系,博士后

1999-2002北京化工大学化学工程系,博士

主讲课程

本科生课程天然药物工程》、林化课程设计和《林化综合实习》;

研究生课程生物技术概论》、《纳米技术概论

科研工作及成果

主要从事生物药物制备、化学修饰及制剂化工程研究;纳米生物材料的设计、构建与应用;新型分离分析介质的设计、合成。 在 Nature NanotechnologyIF 38.986,封面)、 Nano Letters IF 13.779)、ACS Appl Mater & InterfacesIF 7.504)、Journal of Membrane ScienceIF 6.035等国际著名期刊上发表论文约70多篇,其中SCI收录50 多篇。申请中国发明专利50多件,其中授权专利11件。出版译著《纳米生物技术: 概念, 应用和前景》-(8-14); 参加撰写专著《聚乙二醇修饰药物:概念、设计和应用》-(第5章:聚乙二醇—生物大分子偶联物的分析与质量鉴定);参与编写《生化分离介质的制备与应用》图书。主持过国家重点研发计划项目课题、国家863项目、国家自然科学基金项等项目。作为研究小组负责人,与企业合作,获得药物临床批件1项(已通过临床I期研究)。获中国分析测试协会科学技术奖二等奖(省部级,排名第11项。


奖励及荣誉称号

获中国分析测试协会科学技术奖二等奖(省部级,排名第1

学术/社会兼职

Nature集团旗下期刊Scientific Report编委委员

学术成果展示(不超30个)

1. Ge J #, Lei JD #, Zare RN. Protein-inorganic hybrid nanoflowers. Nature Nanotechnology, 2012, 7, 428-432. #共同第1作者(Equal contribution)(IF 38.986,引用316)Cover story(封面文章),被美国Science选为ScienceShot报道,并被美国著名科学家夏幼南教授等在Nature Nanotechnology 期刊上撰文进行新闻和亮点评述(News & Views).

2. Wang, LY; Fang, MQ; Liu, J; He, J; Li, JD; Lei, JD*. Layer-by-Layer Fabrication of High-Performance Polyamide/ZIF-8 Nanocomposite Membrane for Nanofiltration Applications. ACS Applied Materials & Interfaces, 2015, 7(43): 24082-24093.

3. Liu YanxueQi QiLi, XiaominLiu JingWang LuyingHe JingLei Jiandu(*). Self-Assembled Pectin-Conjugated Eight-Arm Polyethylene Glycol-Dihydroartemisinin Nanoparticles for Anticancer Combination Therapy. ACS SUSTAINABLE CHEMISTRY & ENGINEERING2017.959):8097~8107.

4. Dai L, Li D, Cheng J, Liu J, Deng LH, Wang LY, Lei JD* and He J. Water soluble multiarm-polyethylene glycol–betulinic acid prodrugs: design, synthesis, and in vivo effectiveness. Polymer Chemistry, 2014, 5, 5775-5783.

5. Dai L, Yang TY, He J, Deng LH, Liu J, Wang Luying, Lei JD*, Wang LY. Cellulose-graft-poly(L-lactic acid) nanoparticles for efficient delivery of anti-cancer drugs. Journal of Materials Chemistry B, 2014, 2: 6749-6757.

6. Liu, J; He, J; Wang, LY; Li, R; Chen, P; Rao, X; Deng, LH; Rong, L; Lei, JD*. NiO-PTA supported on ZIF-8 as a highly effective catalyst for hydrocracking of Jatropha oil. SCIENTIFIC REPORTS, 2016, 6: 23667.

7. Kefeng Liu, Lin Dai, Chunxiao Li, Jing Liu, Luying Wang and Jiandu Lei*. Self-assembled targeted nanoparticles based on transferrin-modified eight-arm-polyethylene glycol–dihydroartemisinin conjugate. SCIENTIFIC REPORTS, 2016,  6: 29461.

8. Dai, L; Liu, KF; Si, CL; Wang, LY; Liu, J; He, J; Lei, JD *. Ginsenoside nanoparticle: a new green drug delivery system. JOURNAL OF MATERIALS CHEMISTRY B, 2016, 4(3): 529-538.

9. Liu, J; Chen, P; Yao, WJ; Wang, J; Wang, LY; Deng, LH; He, J; Zhang, GF; Lei, JD*. Subcritical water extraction of betulinic acid from birch bark. INDUSTRIAL CROPS AND PRODUCTS, 2015, 74: 557-565.

10. Liu, Jing; Chen, Pan; Deng, Lihong; He, J; Wang, LY; Rong, L; Lei, JD*. A Non-sulfided flower-like Ni-PTA Catalyst that Enhances the Hydrotreatment Efficiency of Plant Oil to Produce Green Diesel. SCIENTIFIC REPORTS, 2015, 5: 15576.

11. Liu, J; Lei, JD*; He, J; Deng, LH; Wang, LY; Fan, K; Rong, L. Hydroprocessing of Jatropha Oil for Production of Green Diesel over Non-sulfided Ni-PTA/Al2O3 Catalyst. SCIENTIFIC REPORTS, 2015, 5: 11327.

12. Dai, L; Liu, KF; Si, CL; He, J; Lei, JD*; Guo, LQ. A novel self-assembled targeted nanoparticle platform based on carboxymethylcellulose co-delivery of anticancer drugs. JOURNAL OF MATERIALS CHEMISTRY B, 2015, 3(32): 6605-6617.

13. Dai L, Cao X, Liu KF, Li CX, Zhang GF, Deng LH, Si CL, He J and Lei JD*. Self-assembled targeted folate-conjugated eight-arm-polyethylene glycol–betulinic acid nanoparticles for co-delivery of anticancer drugs. Journal of Materials Chemistry B, 2015, 3: 3754-3766.

14. Dai L, Wang LY, Deng LH, Liu J, Lei JD*, Li D, He J. Novel multiarm polyethylene glycol- dihydroartemisinin conjugates enhancing therapeutic efficacy in non-small-cell lung cancer. Scientific Reports. 2014, 4: 5871.

15. Liu J, Chen P, He J, Deng LH, Wang LY, Lei JD*, Rong L. Extraction of oil from Jatropha curcas seeds by subcritical fluid extraction. Industrial Crops and Products, 2014, 62: 235-241.

16. Ge J, Lei JD, Zare RN. Bovine serum albumin-poly(methyl methacrylate) nanoparticles: an example of frustrated phase separation. Nano Letters, 2011, 11(6):2551-2554.

17. Kou X; Li Q; Lei JD*, Geng LY; Geng HQ; Zhang GF; Ma GH; Su ZG; Jiang QY. Preparation of molecularly imprinted nanospheres by premix membrane emulsification technique. Journal of Membrane Science. 2012, 417-418: 87-95.

18. Zhai YQ; Zhou WQ; Wei W; Qu JBLei JD*; Su, ZG; Ma, GH. Functional gigaporous polystyrene microspheres facilitating separation of poly(ethylene glycol)-protein conjugate. Analytica Chimica Acta. 201271227):152-161.